Obesity, Insulin resistance And Metabolic Syndrome - Basics of Thin Fat Obesity & Metabolic Surgery
Is obesity a disease? Or is it a lifestyle disorder associated with a high body mass index? - how is it linked to metabolic syndrome and insulin resistance? what is thin fat obesity? do these patients also need bariatric or metabolic surgery? What are the aims of the treatment of morbid obesity? - Watch as Dr. Praveen Raj Palanivelu, Director, Institute of metabolic surgery, GEM Hospital, Coimbatore explains all these points and a few more in this excellent overview of the concepts of obesity and special relevance to thin fat obesity.
As explained in the video, Obesity should be classified based on body composition and it is the abnormal body composition and not isolated body mass index that plays a pathophysiologic role in this disease. The chronic inflammation of adipose tissue leads to an increase in the secretion of cytokines which lead to end-organ effects on the liver, muscle, and adipose tissue, and these three together with increased free fatty acids lead to insulin resistance - This in essence is the basis of metabolic syndrome and its constellation - Diabetes, Hypertension, Polycystic ovarian syndrome, and non-alcoholic fatty liver disease.
Therefore, the treatment aims should be fat loss as well as muscle mass gain as these two together will achieve the desired outcome of treatment in these patients. So, do have a look at this video for understanding the basics of metabolic syndrome and surgery.